Forsker på marin bioteknologi, bioprospektering, enzymidentifisering, enzymoptimalisering, proteinproduksjon og molekylærbiologi. Vi ønsker å tilby bioteknologiske løsninger for den bio-baserte marine industrien. Vårt hovedfokus er på å utvikle enzymer etter industriens behov. Vi jobber derfor med å lete etter nye enzymer, men også å optimalisere eksisterende enzymer. Jobber med metoder som bioprospektering; funksjonell screening av enzymaktivitet; state-of-the-art rekombinant kloning; heterolog uttrykking av proteiner i prokaryote og eukaryote systemer; enzymproduksjon; aktivitetstesting av enzymer; utvikling av enzymassay; proteinrensing; immunoblotting; og lab- og prosjektadministrasjon.
Gro Elin Kjæreng Bjerga
Forskningsleder Marin bioteknologi
grbj@norceresearch.no
+47 56 10 74 04
+47 907 81 736
Nygårdsgaten 112, 5008 Bergen, Norway
Divisjon
Klima og miljø
Forskningstema
Forskergrupper
Mer info om Gro
Prosjekter
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Vitenskapelig artikkelIncreased Thermostability of an Engineered Flavin-Containing Monooxygenase to Remediate Trimethylamine in Fish Protein Hydrolysates– Applied and Environmental Microbiology 2023
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Vitenskapelig artikkelCharacterization of a novel cold-adapted intracellular serine protease from the extremophile Planococcus halocryophilus Or1– Frontiers in Microbiology 2023
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Vitenskapelig artikkelA ShK-like Domain from Steinernema carpocapsae with Bioinsecticidal Potential– Toxins 2022
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Vitenskapelig artikkelSmall, charged proteins in salmon louse (Lepeophtheirus salmonis) secretions modulate Atlantic salmon (Salmo salar) immune responses and coagulation– Scientific Reports 2022
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KonferanseforedragNovel enzymatic strategies to remediate smell in fish protein hydrolysates– Enzymatic protein hydrolysis and bioactive peptides 2022
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Vitenskapelig artikkelThe bone-degrading enzyme machinery: From multi-component understanding to the treatment of residues from the meat industry– Computational and Structural Biotechnology Journal 2021
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Vitenskapelig artikkelTwo-step functional screen on multiple proteinaceous substrates reveals temperature-robust proteases with a broad-substrate range– Applied Microbiology and Biotechnology 2021
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Vitenskapelig artikkelCommunity-Wide Experimental Evaluation of the PROSS Stability-Design Method– Journal of Molecular Biology (JMB) 2021
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Vitenskapelig artikkelDeciphering a Marine Bone-Degrading Microbiome Reveals a Complex Community Effort– mSystems 2021
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Vitenskapelig artikkelFragment exchange (FX) plasmid tools for CRISPR/Cas9-mediated gene integration and protease production in Bacillus subtilis– Applied and Environmental Microbiology 2020
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Vitenskapelig artikkelUse of flavin containing monooxygenases for conversion of trimethylamine in salmon protein hydrolysates– Applied and Environmental Microbiology 2020
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KonferanseforedragTHE SALMON LOUSE (LEPEOPHTHEIRUS SALMONIS) SALIVARY GLAND SECRETES IMMUNE REGULATORY PROTEINS– 19th International Conference on Diseases of Fish and Shellfish 2019
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Vitenskapelig artikkelBioprospecting Reveals Class III ω-Transaminases Converting Bulky Ketones and Environmentally Relevant Polyamines– Applied and Environmental Microbiology 2019
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Vitenskapelig artikkelDecoding the Ocean’s Microbiological Secrets for Marine Enzyme Biodiscovery– FEMS Microbiology Letters 2018
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Vitenskapelig artikkelDevelopment of Versatile Vectors for Heterologous Expression in Bacillus– Microorganisms 2018
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Vitenskapelig artikkelMutational analysis of the pro-peptide of a marine intracellular subtilisin protease supports its role in inhibition– Proteins: Structure, Function, and Bioinformatics 2018
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Vitenskapelig artikkelBiochemical characterization of ParI, an orphan C5-DNA methyltransferase from Psychrobacter arcticus 273-4– Protein Expression and Purification 2018
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Vitenskapelig artikkelDeterminants and Prediction of Esterase Substrate Promiscuity Patterns– Journal of the American Chemical Society 2017
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FagartikkelMikroalger – et nytt råstoff for en bærekraftig oppdrettsnæring– Nf xpert : en spesialutgave av Norsk fiskeoppdrett 2017
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KonferanseforedragSkrott og bein på menyen?– Uni Research Miljø - intern seminarserie 2017
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KonferanseforedragBlue perspectives of NorZymeD: New enzymes are key to future developments in the emerging bio-based industry– NorZymeD annual meeting 2017 2017
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KonferanseforedragNew enzyme tools are key to future developments in the emerging Norwegian marine bio-based industry– BioCat Annual Conference 2017 2017
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Populærvitenskapelig artikkelFiskeben til middag?– Dagens næringsliv 2016
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KonferanseforedragProduction of proteases for industrial applications– P4EU meeting 2016
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KonferanseforedragProtease identification, development and production for industrial applications– Seminar series for doctoral candidates and post-doctoral researchers 2016
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Vitenskapelig artikkelA rapid solubility-optimized screening procedure for recombinant subtilisins in E. coli– Journal of Biotechnology 2016
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Vitenskapelig artikkelRole of residues W228 and Y233 in the structure and activity of metallo-β-lactamase GIM-1– Antimicrobial Agents and Chemotherapy 2016
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Vitenskapelig artikkelEngineering low-temperature expression systems for heterologous production of cold-adapted enzymes– Bioengineered 2016
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Vitenskapelig artikkelCold shock induction of recombinant Arctic environmental genes– BMC Biotechnology 2015
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Vitenskapelig artikkelStructural and biochemical characterization of VIM-26 shows that Leu224 has implications for the substrate specificity of VIM metallo-β-lactamases– The FEBS Journal 2015
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Vitenskapelig artikkelThe PHD finger of p300 influences its ability to acetylate histone and non-histone targets– Journal of Molecular Biology (JMB) 2014
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Vitenskapelig artikkelHis224 alters the R2 drug binding site and Phe218 influences the catalytic efficiency of the metallo-β-lactamase VIM-7– Antimicrobial Agents and Chemotherapy 2014